Symposium C

Paper Title
Hydrogel-based oil-sealed microwell array for analyzing heterogeneity of extracellular vesicles secreted from single cells
Short Biography
Hiroaki Onoe received his Ph.D. in Mechanical Engineering from The University of Tokyo in 2006. After postdoctoral research at The University of Tokyo and UC Berkeley, he joined the Institute of Industrial Science, The University of Tokyo, in 2009. Since 2014, he has been with Keio University, where he is now a Professor of Mechanical Engineering. His research focuses on microfluidics, biofabrication, functional materials, and self-assembly.

Paper Title
Designed lipid-based nanoparticles for biological applications
Short Biography
JSPS Research Fellowship for Young Scientists (DC1), (April 1st, 2019–March 31st, 2021) Graduate School of Chemical Sciences and Engineering Hokkaido University, Japan
Doctor of Philosophy in Engineering, (March 25, 2021) Graduate School of Chemical Sciences and Engineering Hokkaido University, Japan
Assistant Professor, (April 1, 2021–August 31, 2023) Department of Applied Chemistry, Faculty of Engineering Kyushu University, Japan
Senior Assistant Professor, (September 1, 2023–Present) Division of Advanced Mechanical Systems Engineering, Institute of Engineering Tokyo University of Agriculture and Technology, Japan

Paper Title
Extrinsic Photobiomodulation-Activated Signal Transduction Pathways Driving Mesenchymal Stem Cell Differentiation on Microisland Patterns
Short Biography
Meng-Jiy Wang is a Professor at Department of Chemical Engineering, Taiwan Tech (National Taiwan University of Science and Technology). She received her Ph.D. degree from the Univeristé du Maine, Le Mans (now Le Mans University), France, in 2002. She started her career at Taiwan Tech, Taipei, since 2006 after serving four years as a Post-Doctoral Researcher at the Queen Mary University of London, London, U.K. Her research interests include plasma technology, surface modifications, biosensors, and 3D bioprinting.

Paper Title
Micro/nano biomechanical approaches for investigating the cell nuclear mechanotransduction mechanism
Short Biography
Dr. Nagayama received his B.Eng. and M.Eng. degrees from Tohoku University, Japan, and received a PhD degree in 2006 from Nagoya Institute of Technology, Japan. He has been a professor at Ibaraki University, Japan, since 2014. He advances our understanding of the mechanical properties of the cells and how the cells respond to force and deformation. Recently, he has used unique micro/nano manipulation techniques to investigate the mechanical response of intracellular structures, such as cytoskeleton and the cell nucleus. His goal is to develop novel biomedical engineering technologies that control cell motility, proliferation, and gene expression to optimize regenerative tissues.

Paper Title
Energy-Based Interventions for Fibrotic Tissue Remodeling and Senescent Cell Clearance
Short Biography
Ippei Yagi is an Assistant Professor at the Department of Electrical and Electronic Engineering, Faculty of System Design, Tokyo Metropolitan University. He received his Ph.D. in Science from the University of Tokyo in 2014. Before joining academia, he worked as an engineer at GE Healthcare Japan (2014–2020), where he contributed to the development of MRI and ultrasound probes. His research focuses on bioelectronic and plasma-based technologies for therapeutic applications, including pulsed electric fields, electroporation, and the dielectric analysis of cells and tissues.